E. coli outbreak in Europe is super-toxic strain

 Scientists on Thursday blamed Europe's worst recorded food-poisoning outbreak on a "super-toxic" strain of E. coli bacteria that might be brand new.

But while suspicion has fallen on raw tomatoes, cucumbers and lettuce as the source of the germ, researchers have been unable to pinpoint the food responsible for the frightening illness, which has killed at least 18 people, sickened more than 1,600 and spread to least 10 European countries.
An alarming number of victims - about 500 - have developed kidney complications that can be deadly.
Chinese and German scientists analyzed the DNA of the E. coli bacteria and determined that the outbreak was caused by "an entirely new, super-toxic" strain that contains several antibiotic-resistant genes, according to a statement from the BGI laboratory in Shenzhen, China. It said the strain appeared to be a combination of two types of E. coli.
"This is a unique strain that has never been isolated from patients before," Hilde Kruse, a food safety expert at the World Health Organization, said. The new strain has "various characteristics that make it more virulent and toxin-producing" than the many E. coli strains people naturally carry in their intestines.
However, Dr. Robert Tauxe, an expert in food-borne diseases at the U.S. Centers for Disease Control and Prevention, questioned whether the strain is new, saying it had previously caused a single case in Korea in the 1990s. He said genetic fingerprints may vary from specimen to specimen, but that is not necessarily enough to constitute a new strain.
"Though it appears to have been around a while, it hasn't called attention to itself as a major public health problem before," Tauxe said.
Russia extended a ban on vegetables from Spain and Germany to the entire European Union to try to stop the outbreak from spreading east, a move the EU quickly called disproportionate and Italy's farmers denounced as "absurd." No deaths or infections have been reported in Russia.
Some scientists suspect the deadly E. coli might have been in manure used to fertilize vegetables.
Kruse said it is not uncommon for bacteria to evolve and swap genes. It is difficult to explain where the new strain came from, she said, but bacteria from humans and animals easily trade genes.
Previous E. coli outbreaks have mainly hit children and the elderly, but this one is disproportionately affecting adults, especially women. Kruse said there might be something particular about the bacteria strain that makes it more dangerous for adults. Nearly all the sick either live in Germany or recently traveled there.
The outbreak is considered the third-largest involving E. coli in recent history, and it may be the deadliest. Twelve people died in a 1996 Japanese outbreak that reportedly sickened more than 9,000, and seven died in a Canadian outbreak in 2000.

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