Be Careful Of The Potential Risk Of 5α- reductase Inhibitors Used For BPH

According to an article published online by JAMA Internal Medicine, using 5α- reductase inhibitors (5ARIs) was not associated with increased suicide risk in a group of older men but risks for self-harm and depression were increased during the 18 months after medication initiation. 5ARIs is used to treat lower urinary tract symptoms that caused by BPH (benign prostatic hyperplasia) in older men. Though the potential benefits of 5ARIs likely outweigh these risks for most patients, it’s also important to be more careful when using this medicine for curing BPH.



BPH, as a common disease in men over 50, brings a series of unbearable symptoms to male patients, including urinary frequency and urgency, frequent urination at night, difficulty urinating, weak urine stream, dribbling at the end of urination, inability to completely empty the bladder. These urinary symptoms will reduce patients life quality. To have a complete cure, patients shouldn’t take medicines blindly. It’s necessary to follow doctors prescriptions and do some lifestyle changes. 
For patients who take 5ARIs to manage the urinary symptoms, once notice the potential risks of this medicine, a different medication treatment should be used as replacement to prevent the risks. There is a herbal medicine called Diuretic and Anti-inflammatory Pill is effective in treating BPH. It’s made from more than 50 kinds of natural herbs that can work well on resolving the urinary symptoms. It contains semen plantaginis, dianthus superbus and polygonum aviculare, which have properties of inducing diuresis to increase the urine flow and clear the urinary track. Thus, the inflammatory substances can be discharged and thereby the urinary symptoms can be cured gradually.
Except medication treatment, BPH patients should also take measures to minimize the symptoms. Since worry about the symptoms can make them worse, patients should be relax before urinating. And do not limit the intake of fluid to avoid the urination and go to the bathroom immediately if there is an urge. It’s helpful to drink fluids throughout the day to keep hydrated. But don’t drink fluids that can cause frequent urination, such as caffeine and alcohol. Moreover, if you often wake up because you need to urinate, limit your fluid intake in the evening. And empty your bladder before bedtime.

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