How High is the Positive Rate of Prostate Biopsy?
Prostate cancer is a common urinary tumor, but it is often insidious. Since 1986, FDA approved PSA as a tumor marker for monitoring prostate cancer. PSA has always played an important role in the diagnosis and treatment of prostate cancer. In general, The higher the PSA value, the greater the likelihood of prostate cancer. When clinically suspected prostate cancer, prostate biopsy is the most reliable test for the diagnosis of prostate cancer.
Indications for prostate biopsy include: rectal nodules found in prostate nodules; MRI B ultrasound and other imaging findings abnormal; PSA> 10ng / ml; PSA 4-10ng / ml; f / t PSA <0.16. Then What is the positive rate for prostate biopsy?
The incidence of prostate cancer varies greatly among different races and regions. In the United States, the incidence of prostate cancer ranks first in male malignancies. However, thanks to the popularity of PSA screening in the US, 80% of prostate cancer belongs to early localized prostate cancer. And PSA <10ng/ml when most patients with prostate cancer in the United States are diagnosed.
A retrospective analysis of 36,316 cases of prostate puncture revealed that the puncture positive rate was 18.67% when PSA<2ng/ml, and 21.89% when PSA was at 2-2.5ng/ml; PSA 2.5-4 ng/ Ml, when the positive rate of puncture is 27.48%; when PSA is at 4-10ng/ml, the positive rate of puncture is 30.08%.
From January 2000 to June 2005, the puncture positive rate was 18.1% among patients with PSA<4ng/ml; PSA 4-10ng/ml, f/t PSA>0.16ng/ml, the positive rate of puncture was 11.6%; PSA 4-10 ng/ml, f/t PSA <0.16 ng/ml, the positive rate of puncture was 17.4%; PSA 10-20 ng/ml, the positive rate of puncture was 24.9%; PSA>20 ng/ml, the positive rate of puncture is 56.7%.
There are two main reasons for the increase in the positive rate of prostate puncture: the increase in the incidence of prostate cancer caused by diet, environment and other factors, and the continuous improvement of diagnostic methods.
In the same low-incidence area of prostate cancer, the positive rate of prostate puncture in Korea is similar to that in China. According to reports, for Koreans with PSA levels between 4-10 ng/ml, the positive rate of puncture is 15.9%, while the positive rate of puncture in Japan is higher. In China, Korea and Japan, Japanese studies have shown that the positive rates of prostate cancer puncture are 26.3% and 34.3% when PSA is at 3-4 ng/ml and 4-10 ng/ml, respectively.
It can be seen that due to the low prevalence of prostate cancer among Chinese men, the positive rate of puncture at low PSA level is relatively low. With the increasing prevalence of prostatitis, Wuhan Dr.Lee TCM Clinic has developed a granular Chinese medicine that meets modern needs - Diuretic and Anti-inflammatory Pill.
Unlike the chemical treatment of prostate diseases with common anti-inflammatory medicine, Diuretic and Anti-Inflammatory Pill can comprehensively improve the internal and external state of the prostate, eliminate inflammation, and achieve the rehabilitation of the prostate. It solves the problem of pharmaceutical ingredients penetration and absorption, with direct pathological improvement of the diseased prostate, so the patients can be quickly cured. It is recommended that the patient get early diagnosis and timely treatment to avoid long term sufferings.
