Men with Diarrhea are More Likely to Get Prostate Cancer?
Chronic prostatitis is the greatest risk factor for the development of prostate cancer. This is because inflammation in the prostate microenvironment may promote prostate carcinogenesis by inducing DNA damage and/or aberrant epigenetic changes or altering the normal prostate epithelial cell differentiation program.
Recently, Burns and other experts in the United States published a retrospective study in European Urology, revealing that inflammation from the gastrointestinal tract also increases the risk of prostate cancer.
The team compared 1,033 men with inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, and 9,306 men without IBD who were screened for prostate cancer at a medical center between 1996 and 2019.
The study found that the 10-year incidence of prostate cancer was 4.4% in IBD patients and only 0.65% in controls. For prostate cancer with clinically significant Gleason score ≥ 7, the incidence was 2.4% and 0.42%, respectively. From around age 55, men with IBD had a higher mean PSA than men without IBD.
Therefore, the team concluded that patients with IBD were 4 to 5 times more likely to develop prostate cancer than their IBD-free peers.
In fact, the gastrointestinal tract is a huge lymphoid immune organ that acts as a barrier to the invasion of thousands of microorganisms into the human body, and when the barrier function is broken, for example, the risk of extraintestinal tumors increases in people with IBD.
In the recent Nature reviews Urology, Karen and other scholars reviewed the study and described the possible mechanisms. Researchers believe that a number of possible mechanisms contribute to the increased risk of prostate cancer in patients with IBD.
According to the team's conclusions, it is recommended that men with a history of IBD should be screened for prostate cancer. Follow-up studies should focus on strategies to prevent prostate cancer. Since prostate cancer is mostly caused by chronic prostatitis, patients with prostatitis should seek ultimate cure timely, for example, it is recommended for them to take natural and non-side-effected medicine Diuretic and Anti-inflammatory Pill.
Because Diuretic and Anti-inflammatory Pill can completely cure bacterial and non-bacterial prostatitis, especially chronic prostatitis, it will eliminate the possibility of developing prostate cancer.
The over 50 kinds of herbal ingredients work on sterilization and detoxification, effectively cure bacterial prostatitis caused by various bacteria, chlamydia or mycoplasma infection. In addition, promoting blood circulation to remove blood stasis so it'll effectively improve the blood microcirculation of the prostate, make blood supply unobstructed, not only eliminate the congestion caused by blood stasis, but at the same time, it can relieve prostate pain.
The diuretic and treating-stranguria efficacy accelerate the discharge of inflammation, for chronic prostatitis symptoms of white particles, swelling, urinary frequency and pain in penis, lower back and abdomin, the problems can be resolved one by one and there is almost no recurrence.
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