Prostate-specific antigen (PSA) is a single-chain glycoprotein secreted by the prostate, which exists in the epithelial cells of the prostate duct. In the examination of prostate cancer, PSA serum level is significantly increased. At the same time, a high concentration of PSA in the blood test is also a signal of inflammation.
Recently, researchers from the School of Stomatology, the Institute of Urology and the Department of Pathology of Affiliated Hospital of Case Western Reserve University in the United States have found that the treatment of periodontal diseases can alleviate the symptoms of prostatitis.
Previous studies have found a link between periodontal disease and prostatitis: periodontal disease can activate glands that produce semen, leading to difficulty in urinating.
Nabil, the study's correspondent, said that timely treatment of periodontal diseases could alleviate the symptoms of prostatitis and improve the quality of life of prostatitis patients. The results were published in Dentistry. Timely treatment of the periodontal disease can improve the symptoms of prostatitis and reduce the concentration of PSA in men with high PSA concentration and men with chronic periodontitis.
Nabil also explained that periodontal disease not only affects the oral cavity but also causes inflammation in various systems. Previous studies have also found a link between periodontal disease and rheumatoid arthritis, heart disease and some fatal diseases.
Researchers selected 27 men aged over 21 years old to participate in the study. Each participant underwent acupuncture biopsy of the prostate in the past year to confirm whether there was inflammation in the prostate. First, the symptoms of prostate diseases were evaluated. IPSS (International Prostate Symptom Score) was used to understand their quality of life and urination through the Internet.
Of the 27 subjects, 21 had no or mild inflammation, but 15 had biopsy results suggesting malignant prostate tumors. Two of them coexisted with inflammation and malignant tumors. The subjects with at least 18 teeth underwent oral examinations at the same time. To confirm whether they have periodontal disease, symptoms were examined, including periodontal inflammation, bleeding, tooth loss, and bone loss.
The results showed that all subjects had moderate to severe periodontal disease. Four to eight weeks later, the patients were re-examined after the corresponding periodontal treatment. The results showed that the oral condition of the subjects had improved significantly. During the 4 to 8 weeks of oral care, the subjects did not receive any treatment for the prostate. But even without treatment, the decline of PSA levels is still found in 21 subjects.
The subjects with the highest inflammation index benefited most from periodontal treatment and oral care, as IPSS tests show. But six of them did not change at all, and the results of the IPSS test did not show any improvements. Nabil is conducting a follow-up trial to support the results of the first trial.
He hoped that the treatment of periodontal diseases could be a standard procedure for prostate disease treatment, just as patients with heart disease had to undergo oral examinations before undergoing heart surgery, and pregnant women and pregnant women had to undergo regular oral examinations. Thus, oral periodontal therapy may become an adjuvant therapy to prevent and improve prostatic diseases.
In addition, patients with prostatitis can also take Diuretic and Anti-inflammatory Pill for conservative treatment, which can help to enhance the thoroughness of surgical treatment, prevent complications and recurrence without side effects, it can clear away heat and toxic material, promoting diuresis and relieving stranguria, and it can also improve the immunity of patients. Finally, best wishes for your recovery!